Article
Pharmacogenetic methods as a complement to therapeutic monitoring of antidepressants and neuroleptics.
Therapeutic drug monitoring - 1 Feb 2000
Dahl M L, Sjöqvist F
Abstract excerpt
A short review of the metabolism of psychoactive drugs and the pharmacogenetic factors regulating the enzymes involved is presented here. The potential clinical usefulness of phenotyping and genotyping individuals, with regard to their drug metabolic capacity, is discussed. Indications for genotyping CYP2D6 and a flow scheme for the combined use of conventional therapeutic drug monitoring (TDM) and...
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