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Article

DNA repair polymorphisms XRCC1 and MGMT and risk of adult gliomas.

Neuroepidemiology - 1 Jan 2007

Felini Martha J, Olshan Andrew F, Schroeder Jane C, North Kari E, Carozza Susan E, Kelsey Karl T, Liu Mei, Rice Terri, Wiencke John K, Wrensch Margaret R

Abstract excerpt

X-ray cross complementing group 1 (XRCC1) and O6-methylguanine-DNA methyltransferase (MGMT) are pivotal repair genes focused on repairing lesions due to ionizing radiation, alkylating agents, and oxidative DNA damage, risk factors previously linked to gliomas. Using the population based San Francisco Adult Glioma study, we evaluated associations between XRCC1 Arg399Gln, MGMT Leu84Phe, and MGMT Ile143Val...

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Source

Identifiers

PMID: 17898525
DOI: 10.1159/000108919

Genes

MGMT
XRCC1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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