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Article

Association between XRCC1 polymorphism 399 G->A and glioma among Caucasians: a systematic review and meta-analysis.

BMC medical genetics - 26 Oct 2012

Jacobs Daniel I, Bracken Michael B

Abstract excerpt

BACKGROUND: The x-ray cross complementing group 1 gene (XRCC1) is crucial to proper repair of DNA damage such as single-strand DNA breaks. A non-synonymous polymorphism in XRCC1, 399 G → A, has been shown to reduce effectiveness of such DNA repair and has been associated with the risk of certain cancers. The known risk for glioma from high dose ionizing radiation makes associations between this polymorphism and...

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Source

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Identifiers

PMID: 23101479
DOI: 10.1186/1471-2350-13-97
PMCID: PMC3560258

Genes

XRCC1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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