Article
Association between XRCC1 polymorphisms and glioma risk among Chinese population.
Medical oncology (Northwood, London, England) - 1 Oct 2014
Li Jiang, Qu Qiang, Qu Jian, Luo Wei-Ming, Wang Shang-Yuan, He You-Zhi, Luo Qi-Shan, Xu Yu-Xia, Wang Yong-Fu
Abstract excerpt
The pathogenesis of glioma remains largely unknown now. It has been suggested that the X-ray cross-complementing group 1 (XRCC1) gene may influence the capacity to repair DNA damage leading to an increased gliomas susceptibility. This study aimed to evaluate the relationship between XRCC1 polymorphisms and glioma risk. Genotypes were assessed in 368 Chinese glioma patients and 346 healthy controls. XRCC1...
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