Transgenic enrichment of cardiomyocytes from human embryonic stem cells.

doi:10.1038/sj.mt.6300303

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Article

Transgenic enrichment of cardiomyocytes from human embryonic stem cells.

Molecular therapy : the journal of the American Society of Gene Therapy - 1 Nov 2007

Anderson David, Self Tim, Mellor Ian R, Goh Gareth, Hill Stephen J, Denning Chris

Abstract excerpt

To realize the full scientific and clinical potential of human embryonic stem cell (hESC)-cardiomyocytes, strategies to overcome the high degree of heterogeneity of differentiated populations are required. Here we demonstrate the utility of two transgenic approaches in enrichment of cardiomyocytes derived from HUES-7 cells: (i) negative selection of proliferating cells with the herpes simplex virus thymidine...

Topics

Cell Line
Cell Separation
Embryonic Stem Cells
Humans
Myocytes, Cardiac
Oligonucleotide Array Sequence Analysis
Phenotype
Transgenes

Source

Open in PubMed

Identifiers

PMID: 17895862
DOI: 10.1038/sj.mt.6300303

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026.

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