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Article

Functional cardiomyocytes derived from human induced pluripotent stem cells.

Circulation research - 27 Feb 2009

Zhang Jianhua, Wilson Gisela F, Soerens Andrew G, Koonce Chad H, Yu Junying, Palecek Sean P, Thomson James A, Kamp Timothy J

Abstract excerpt

Human induced pluripotent stem (iPS) cells hold great promise for cardiovascular research and therapeutic applications, but the ability of human iPS cells to differentiate into functional cardiomyocytes has not yet been demonstrated. The aim of this study was to characterize the cardiac differentiation potential of human iPS cells generated using OCT4, SOX2, NANOG, and LIN28 transgenes compared to human embryonic...

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Source

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Identifiers

PMID: 19213953
DOI: 10.1161/CIRCRESAHA.108.192237
PMCID: PMC2741334

Genes

NANOG
SOX2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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