Article
Estrogen receptor alpha and beta gene polymorphisms are not risk factors for recurrent miscarriage in a Brazilian population.
Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis - 1 Apr 2008
Aléssio Aline Morandi, Siqueira Lúcia Helena, de Carvalho Egle Cristina Couto, Barini Ricardo, Mansur Antônio de Pádua, Hoehr Nelci Fenalti, Annichino-Bizzacchi Joyce Maria
Abstract excerpt
The aim of this study was to determine the prevalence of alpha (ESR1: c.454-397T>C and c.454-351A>G) and beta (ESR2: 1082G>A and 1730G>A) estrogen receptor gene polymorphisms in 2 Brazilian ethnic groups (Caucasian, African Brazilian) and to investigate their association with recurrent miscarriage (RM) in 75 women with a history of 3 or more consecutive pregnancy losses and 139 controls with at least 2 live...
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