Article
Estrogen receptor beta gene polymorphisms and risk of recurrent pregnancy loss: a case-control study.
Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology - 1 Jan 2015
Kim Jin Ju, Choi Young Min, Lee Sung Ki, Yang Kwang Moon, Paik Eun Chan, Jeong Hyeon Jeong, Jun Jong Kwan, Han Ae Ra, Hwang Kyu Ri, Hong Min A
Abstract excerpt
Estrogen might play a key role in the maintenance of pregnancy. We investigated the role of the ER-β gene +1730 G/A, +1082 G/A, and CA repeat polymorphisms in Korean patients with recurrent pregnancy loss (RPL). Genotyping was performed using the TaqMan assay in 305 patients with at least two unexplained consecutive spontaneous miscarriages before 20 weeks of gestation and 299 controls. The genotype distributions...
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