Article
Association between bronchodilating response to short-acting beta-agonist and non-synonymous single-nucleotide polymorphisms of beta-adrenoceptor gene.
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology - 1 Sept 2005
Cho S-H, Oh S-Y, Bahn J-W, Choi J-Y, Chang Y-S, Kim Y-K, Min K-U, Kim Y-Y
Abstract excerpt
BACKGROUND: With beta-agonists being the most widely used agents in the treatment of asthma, in vitro studies reported that beta(2)-adrenergic receptor (ADRB2) polymorphisms are associated with agonist-promoted down-regulation. OBJECTIVE: The present population-based study aimed to evaluate the association between bronchodilating response to inhaled short-acting beta-agonist and two non-synonymous...
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