Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The Enigmatic Role of Viruses in Multiple Sclerosis: Molecular Mimicry or Disturbed Immune Surveillance?

Trends in immunology - 1 Jul 2017

Geginat Jens, Paroni Moira, Pagani Massimiliano, Galimberti Daniela, De Francesco Raffaele, Scarpini Elio, Abrignani Sergio

Abstract excerpt

Multiple sclerosis (MS) is a T cell driven autoimmune disease of the central nervous system (CNS). Despite its association with Epstein-Barr Virus (EBV), how viral infections promote MS remains unclear. However, there is increasing evidence that the CNS is continuously surveyed by virus-specific T cells, which protect against reactivating neurotropic viruses. Here, we discuss how viral infections could lead to...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Central Nervous System
Share to Epstein-Barr Virus Infections

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Herpesvirus 4, Human

Share to Immunologic Surveillance

Share to Molecular Mimicry

Share to Receptors, Cytokine

Share to Th1 Cells

Share to Th17 Cells

Source

Open in PubMed Open full text

Identifiers

PMID: 28549714
DOI: 10.1016/j.it.2017.04.006
PMCID: PMC7185415

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The Enigmatic Role of Viruses in Multiple Sclerosis: Molecular Mimicry or Disturbed Immune Surveillance?PMID 28549714Read ↗

The CD8 T Cell-Epstein-Barr Virus-B Cell Trialogue: A Central Issue in Multiple Sclerosis PathogenesisSemantic proximity Read ↗

Trigger, pathogen, or bystander: the complex nexus linking Epstein- Barr virus and multiple sclerosis.Semantic proximity Read ↗

Cumulative Roles for Epstein-Barr Virus, Human Endogenous Retroviruses, and Human Herpes Virus-6 in Driving an Inflammatory Cascade Underlying MS Pathogenesis.Semantic proximity Read ↗

Viruses and endogenous retroviruses in multiple sclerosis: From correlation to causationSemantic proximity Read ↗

Epstein Barr Virus Exploits Genetic Susceptibility to Increase Multiple Sclerosis RiskSemantic proximity Read ↗

New immunopathologic insights into multiple sclerosis.Semantic proximity Read ↗

HSV-1 and Endogenous Retroviruses as Risk Factors in DemyelinationSemantic proximity Read ↗

Endogenous retroviruses in multiple sclerosis: A network-based etiopathogenic modelSemantic proximity Read ↗

Immunology of multiple sclerosis.Semantic proximity Read ↗

The Essential Role of Epstein-Barr Virus in the Pathogenesis of Multiple SclerosisSemantic proximity Read ↗

The immunology of multiple sclerosis.Semantic proximity Read ↗

Multiple Sclerosis between Genetics and Infections: Human Endogenous Retroviruses in Monocytes and MacrophagesSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.