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Article

CD147 stimulates HIV-1 infection in a signal-independent fashion.

Biochemical and biophysical research communications - 23 Nov 2007

Pushkarsky Tatiana, Yurchenko Vyacheslav, Laborico Alicia, Bukrinsky Michael

Abstract excerpt

CD147 is a type I transmembrane protein previously identified as a signal transducing receptor for extracellular cyclophilins. CD147-expressing cells exhibit a characteristic activation of extracellular-signal regulated kinase 1 and 2 (ERK1/2) in response to stimulation with cyclophilin A (CypA). CD147 was also shown to enhance HIV-1 infection in a CypA-dependent fashion, but the role of signaling in this...

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Identifiers

PMID: 17888876
DOI: 10.1016/j.bbrc.2007.08.192
PMCID: PMC2080668

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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