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Article

Regulation of CD147 cell surface expression: involvement of the proline residue in the CD147 transmembrane domain.

The Journal of biological chemistry - 29 Apr 2005

Yurchenko Vyacheslav, Pushkarsky Tatiana, Li Jian-Hua, Dai Wei Wei, Sherry Barbara, Bukrinsky Michael

Abstract excerpt

CD147, also known as extracellular matrix metalloproteinase inducer, is a regulator of matrix metalloproteinase production and serves as a signaling receptor for extracellular cyclophilins. Here we demonstrate that the cell surface expression of CD147 is regulated by cyclophilins via the transmembrane domain of CD147. Solution binding experiments demonstrated that the transmembrane domain was both necessary and...

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Identifiers

PMID: 15671024
DOI: 10.1074/jbc.M412851200

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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Regulation of CD147 cell surface expression: involvement of the proline residue in the CD147 transmembrane domain.PMID 15671024Read ↗

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