Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Optimization of production of monacolin K from gamma-irradiated Monascus mutant by use of response surface methodology.

Journal of medicinal food - 1 Sept 2007

Suh Soo Hwan, Rheem Sungsue, Mah Jae-Hyung, Lee Woosun, Byun Myung-Woo, Hwang Han-Joon

Abstract excerpt

Monascus isolate number 711, which is capable of producing monacolin K as an inhibitor of 3-hydroxy-3-methylglutaryl-coenzyme A reductase, the key enzyme of cholesterol synthesis, was isolated from Ang-kak, the red yeast rice koji. To increase the monacolin K-producing activity of the strain, spore suspensions of the strain were subjected to gamma-irradiation. One thousand mutants were generated via...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Chromatography, High Pressure Liquid
Share to Culture Media

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Gamma Rays

Share to Glycine max

Share to Hordeum

Share to Hydroxymethylglutaryl-CoA Reductase Inhibitors

Share to Lovastatin

Share to Spores, Fungal

Source

Identifiers

PMID: 17887933
DOI: 10.1089/jmf.2006.097

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Optimization of production of monacolin K from gamma-irradiated Monascus mutant by use of response surface methodology.PMID 17887933Read ↗

Enhanced Monacolin K Production in Monascus purpureus Via Mutagenesis and Nitrogen Source Optimization.Semantic proximity Read ↗

Modified mutation method for screening low citrinin-producing strains of Monascus purpureus on rice culture.Semantic proximity Read ↗

Enhancement of yellow pigment production by intraspecific protoplast fusion of Monascus spp. yellow mutant (ade(-)) and white mutant (prototroph).Semantic proximity Read ↗

Optimization of the hongqu starter preparation process for the manufacturing of red mold rice with high gamma-aminobutyric acid production by solid-state fermentation.Semantic proximity Read ↗

Development and screening of mutants from Monascus sanguineus for secondary metabolites productionSemantic proximity Read ↗

Bimutation breeding of Aspergillus niger strain for enhancing β-mannanase production by solid-state fermentation.Semantic proximity Read ↗

Elevated yield of monacolin K in Monascus purpureus by fungal elicitor and mutagenesis of UV and LiCl.Semantic proximity Read ↗

Azaphilone pigments from a yellow mutant of the fungus Monascus kaoliang.Semantic proximity Read ↗

Construction of a Bacillus subtilis (natto) with high productivity of vitamin K2 (menaquinone-7) by analog resistance.Semantic proximity Read ↗

Efficient production of menaquinone (vitamin K2) by a menadione-resistant mutant of Bacillus subtilis.Semantic proximity Read ↗

A plate method for rapid screening of Ketogulonicigenium vulgare mutants for enhanced 2-keto-l-gulonic acid production.Semantic proximity Read ↗

Semisynthesis of novel monacolin J derivatives: hypocholesterolemic and neuroprotective activities.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.