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Article

The mouse homeobox gene Noto regulates node morphogenesis, notochordal ciliogenesis, and left right patterning.

Proceedings of the National Academy of Sciences of the United States of America - 2 Oct 2007

Beckers Anja, Alten Leonie, Viebahn Christoph, Andre Philipp, Gossler Achim

Abstract excerpt

The mouse homeobox gene Noto represents the homologue of zebrafish floating head (flh) and is expressed in the organizer node and in the nascent notochord. Previous analyses suggested that Noto is required exclusively for the formation of the caudal part of the notochord. Here, we show that Noto is also essential for node morphogenesis, controlling ciliogenesis in the posterior notochord, and the establishment of...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 17884984
DOI: 10.1073/pnas.0704344104
PMCID: PMC2000419

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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