Article
A homeobox gene essential for zebrafish notochord development.
Nature - 9 Nov 1995
Talbot W S, Trevarrow B, Halpern M E, Melby A E, Farr G, Postlethwait J H, Jowett T, Kimmel C B, Kimelman D
Abstract excerpt
The notochord is a midline mesodermal structure with an essential patterning function in all vertebrate embryos. Zebrafish floating head (flh) mutants lack a notochord, but develop with prechordal plate and other mesodermal derivatives, indicating that flh functions specifically in notochord development. We show that floating head is the zebrafish homologue of Xnot, a homeobox gene expressed in the amphibian...
Read the complete abstract on PubMedTopics
- Amino Acid Sequence
- Animals
- Base Sequence
- Cell Differentiation
- Chromosome Mapping
- DNA Primers
- DNA-Binding Proteins