Article
A homeobox gene essential for zebrafish notochord development.
Nature - 9 Nov 1995
Talbot W S, Trevarrow B, Halpern M E, Melby A E, Farr G, Postlethwait J H, Jowett T, Kimmel C B, Kimelman D
Abstract excerpt
The notochord is a midline mesodermal structure with an essential patterning function in all vertebrate embryos. Zebrafish floating head (flh) mutants lack a notochord, but develop with prechordal plate and other mesodermal derivatives, indicating that flh functions specifically in notochord deve...
Topics
- Amino Acid Sequence
- Animals
- Base Sequence
- Cell Differentiation
- Chromosome Mapping
- DNA Primers
- DNA-Binding Proteins
- Gastrula
- Genes, Homeobox
- Genes, Lethal
- Hedgehog Proteins
- Homeodomain Proteins
- Humans
- Mesoderm
- Molecular Sequence Data
- Motor Neurons
- Mutation
- Notochord