Article
Association of Pro12Ala polymorphism in the peroxisome proliferator-activated receptor gamma2 gene with small dense low-density lipoprotein in the general population.
Metabolism: clinical and experimental - 1 Oct 2007
Hamada Taku, Kotani Kazuhiko, Tsuzaki Kokoro, Sano Yoshiko, Murata Takashi, Tabata Masahiko, Sato Shigeaki, Sakane Naoki
Abstract excerpt
The Pro12Ala polymorphism of the peroxisome proliferator-activated receptor gamma2 (PPARgamma2) gene has been reported to predict a lower risk for developing type 2 diabetes mellitus. However, its effect on the lipid profile has been disputable. Among low-density lipoproteins, small dense low-density lipoprotein (sdLDL) particles have been linked to a greater risk for coronary artery disease. The purpose of this...
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