Article
Association of peroxisome proliferator-activated receptorgamma gene Pro12Ala and C161T polymorphisms with metabolic syndrome.
Circulation journal : official journal of the Japanese Circulation Society - 1 Apr 2008
Dongxia Liu, Qi Hua, Lisong Liu, Jincheng Guo
Abstract excerpt
UNLABELLED: BACKGROUND Peroxisome proliferator-activated receptor gamma (PPARgamma) is involved mainly in adipocyte differentiation and has been suggested to play an important role in the pathogenesis of insulin resistance (IR) and atherosclerosis. The frequencies of 2 common polymorphisms of the PPARgamma gene, Pro12Ala single nucleotide polymorphism (SNP) in exon B and C161T SNP in exon 6, were investigated in...
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