Article
The BMEI0216 gene of Brucella melitensis is required for internalization in HeLa cells.
Microbial pathogenesis - 1 Jan 2008
Hernández-Castro Rigoberto, Verdugo-Rodríguez Antonio, Puente José Luis, Suárez-Güemes Francisco
Abstract excerpt
Brucella is an intracellular facultative bacterium able to survive and multiply in professional and non-professional phagocytes. However, its adhesion and invasion mechanisms have not been elucidated yet. In this work, we assess the interruption of a BMEI0216 gene of Brucella melitensis, by using HeLa epithelial cells and murine macrophages for invasion and replication assays. The mutation did not affect survival...
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