Article
TLR4 on follicular dendritic cells: an activation pathway that promotes accessory activity.
Journal of immunology (Baltimore, Md. : 1950) - 1 Oct 2007
El Shikh Mohey Eldin M, El Sayed Rania M, Wu Yongzhong, Szakal Andras K, Tew John G
Abstract excerpt
Microbial molecular patterns engage TLRs and activate dendritic cells and other accessory cells. Follicular dendritic cells (FDCs) exist in resting and activated states, but are activated in germinal centers, where they provide accessory function. We reasoned that FDCs might express TLRs and that...
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