Article
Distinct contributions of beta 4GalNAcTA and beta 4GalNAcTB to Drosophila glycosphingolipid biosynthesis.
Glycoconjugate journal - 1 Feb 2008
Stolz Anita, Haines Nicola, Pich Andreas, Irvine Kenneth D, Hokke Cornelis H, Deelder André M, Gerardy-Schahn Rita, Wuhrer Manfred, Bakker Hans
Abstract excerpt
Drosophila melanogaster has two beta4-N-acetylgalactosaminyltransferases, beta4GalNAcTA and beta4GalNAcTB, that are able to catalyse the formation of lacdiNAc (GalNAcbeta,4GlcNAc). LacdiNAc is found as a structural element of Drosophila glycosphingolipids (GSLs) suggesting that beta4GalNAcTs cont...
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