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Article

Distinct contributions of beta 4GalNAcTA and beta 4GalNAcTB to Drosophila glycosphingolipid biosynthesis.

Glycoconjugate journal - 1 Feb 2008

Stolz Anita, Haines Nicola, Pich Andreas, Irvine Kenneth D, Hokke Cornelis H, Deelder André M, Gerardy-Schahn Rita, Wuhrer Manfred, Bakker Hans

Abstract excerpt

Drosophila melanogaster has two beta4-N-acetylgalactosaminyltransferases, beta4GalNAcTA and beta4GalNAcTB, that are able to catalyse the formation of lacdiNAc (GalNAcbeta,4GlcNAc). LacdiNAc is found as a structural element of Drosophila glycosphingolipids (GSLs) suggesting that beta4GalNAcTs contribute to the generation of GSL structures in vivo. Mutations in Egghead and Brainaic, enzymes that generate the...

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PMID: 17876704
DOI: 10.1007/s10719-007-9069-5

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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