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Article

The mutagenic properties of BrdUTP in a random mutagenesis process.

Molecular biology reports - 1 Dec 2008

Ma Xiangdong, Ke Tao, Mao Peihong, Jin Xiang, Ma Lixin, He Guangyuan

Abstract excerpt

To explore the mutagenic properties of the nucleotide analogue bromodeoxyuridine triphosphate (BrdUTP), the wild type alpha-amylase (xamy) gene from Xanthomonas campestris pv. campestris 8004 was used as a mutational target. It was mutated using PCR techniques to partially replace deoxythymidine triphosphate (dTTP) with BrdUTP. A total of 18 mutants were selected for DNA sequencing from the mutagenesis libraries...

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Identifiers

PMID: 17874205
DOI: 10.1007/s11033-007-9137-8

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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