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Article

Wnt signaling pathway analysis in renal cell carcinoma in young patients.

Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc - 1 Dec 2007

Bruder Elisabeth, Moch Holger, Ehrlich David, Leuschner Ivo, Harms Dieter, Argani Pedram, Briner Jakob, Graf Norbert, Selle Barbara, Rufle Alex, Paulussen Michael, Koesters Robert

Abstract excerpt

Renal cell carcinomas in young patients constitute a morphologically and genetically heterogeneous group. Twenty percent belong to the newly recognized Xp11.2 translocation-associated family and rare tumors arise from nephroblastoma. Aberrant Wnt signaling through beta-catenin mutation has been implicated in nephroblastoma pathogenesis and has been found to synergize with WT1 mutations. To characterize Wnt...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 17873895
DOI: 10.1038/modpathol.3800957

Genes

CTNNB1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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