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Article

Biosynthesis of the earthy odorant geosmin by a bifunctional Streptomyces coelicolor enzyme.

Nature chemical biology - 1 Nov 2007

Jiang Jiaoyang, He Xiaofei, Cane David E

Abstract excerpt

Geosmin is responsible for the characteristic odor of moist soil, as well as off-flavors in drinking water and foodstuffs. Geosmin is generated from farnesyl diphosphate (FPP, 2) by an enzyme that is encoded by the SCO6073 gene in the soil organism Streptomyces coelicolor A32 (ref. 3). We have now shown that the recombinant N-terminal half of this protein catalyzes the Mg2+-dependent cyclization of FPP to...

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Identifiers

PMID: 17873868
DOI: 10.1038/nchembio.2007.29
PMCID: PMC3013058

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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