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Article

Morphogen Receptor Genes and Metamorphogenes

1 Nov 2007

Abstract excerpt

Morphogen receptors are nodal points in signal transduction pathways that regulate morphogenesis during embryonic development. A recent discovery identified a recurrent missense mutation in a gene encoding a morphogen receptor responsible for the elusive process of skeletal metamorphosis in humans. Metamorphosis, the postnatal transformation of one normal tissue or organ system into another, is a biological...

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PMID: 17872396
DOI: 10.1196/annals.1402.039

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