Article
Distribution of detoxifying genes polymorphism in Maharastrian population of central India.
Chemosphere - 1 Feb 2008
Saravana Devi Sivanesan, Vinayagamoorthy Nadimuthu, Agrawal Meenal, Biswas Arup, Biswas Raka, Naoghare Pravin, Kumbhakar Sreya, Krishnamurthi Kannan, Hengstler Jan G, Hermes Matthias, Chakrabarti Tapan
Abstract excerpt
The present study is aimed at evaluating the genotype frequency of detoxifying genes such as GSTM1, GSTT1 and NQO1 in Maharastrian population of central India. The study revealed about 64.6% of GSTM1-positive and 35.4% GSTM1-null population. GSTT1-positive genotype was found to be 87.5% and GSTT1-null showed 12.5%. The NQO1 genotype of Maharastrian population showed 52.3% of C/C, 42.48% C/T and 5.18% T/T. The...
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