Article
Sequence distribution of acetaldehyde-derived N2-ethyl-dG adducts along duplex DNA.
Chemical research in toxicology - 1 Oct 2007
Matter Brock, Guza Rebecca, Zhao Jianwei, Li Zhong-ze, Jones Roger, Tretyakova Natalia
Abstract excerpt
Acetaldehyde (AA) is the major metabolite of ethanol and may be responsible for an increased gastrointestinal cancer risk associated with alcohol beverage consumption. Furthermore, AA is one of the most abundant carcinogens in tobacco smoke and induces tumors of the respiratory tract in laborator...
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