Article
[Recent advances in bladder urothelial carcinogenesis].
Bulletin du cancer - 1 Dec 2015
Pignot Géraldine, le Goux Constance, Bieche Ivan
Abstract excerpt
Bladder cancer is the sixth cause of cancer mortality in France and prognosis of muscle-invasive tumors remains poor due to lack of effective treatments. Recent advances in molecular biology applied to tumors and results of recent genome-wide studies have brought a important impact on the understanding of bladder carcinogenesis. Main molecular alterations concern FGFR3, TP53 and HER2, and it is now possible to...
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