Article
[Investigation of the mutational status of the FGFR3 gene in urothelial bladder carcinoma].
Arkhiv patologii - 1 Jan 2023
Oliushina E M, Zavalishina L E, Alekseenok E Yu, Oskina N A, Andreeva Yu Yu, Kuznetsova O A, Filipenko M L, Frank G A
Abstract excerpt
OBJECTIVE: To study the somatic mutational status of the FGFR3 gene in urothelial bladder cancer (BC) and evaluate its relationship with the clinical and morphological characteristics of the tumor, deficiency of the DNA mismatch repair (dMMR), PD-L1 tumor status, and immunohistochemical (IHC) expression of the p16 protein. MATERIAL AND METHODS: Surgical material of 40 patients with BC, on which the mutational...
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