Article
Critical roles of Sp1 in gene expression of human and rat H+/organic cation antiporter MATE1.
American journal of physiology. Renal physiology - 1 Nov 2007
Kajiwara Moto, Terada Tomohiro, Asaka Jun-ichi, Ogasawara Ken, Katsura Toshiya, Ogawa Osamu, Fukatsu Atsushi, Doi Toshio, Inui Ken-ichi
Abstract excerpt
A H+/organic cation antiporter (multidrug and toxin extrusion 1: MATE1/SLC47A1) plays important roles in the tubular secretion of various clinically important cationic drugs such as cimetidine. We have recently found that the regulation of this transporter greatly affects the pharmacokinetic prop...
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