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Article

Functional characterization of NF-kappaB inhibitor-like protein 1 (NFkappaBIL1), a candidate susceptibility gene for rheumatoid arthritis.

Human molecular genetics - 15 Dec 2007

Greetham Darren, Ellis Charles D, Mewar Devesh, Fearon Ursula, an Ultaigh Sinead Nic, Veale Douglas J, Guesdon François, Wilson Anthony G

Abstract excerpt

Several studies have implicated the NF-kappaB inhibitor-like protein 1 (NFkBIL1) gene located in the class III region of the major histocompatibility complex (MHC) as a possible susceptibility locus for rheumatoid arthritis (RA). Based on limited homology, it has been suggested to be a member of the inhibitor of NF-kappaB (IkappaB) family of proteins, but a role in mRNA processing has also been proposed. We have...

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PMID: 17855452
DOI: 10.1093/hmg/ddm261

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