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Article

30 Years of NF-κB: A Blossoming of Relevance to Human Pathobiology.

Cell - 12 Jan 2017

Zhang Qian, Lenardo Michael J, Baltimore David

Abstract excerpt

NF-κB was discovered 30 years ago as a rapidly inducible transcription factor. Since that time, it has been found to have a broad role in gene induction in diverse cellular responses, particularly throughout the immune system. Here, we summarize elaborate regulatory pathways involving this transcription factor and use recent discoveries in human genetic diseases to place specific proteins within their relevant...

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Identifiers

PMID: 28086098
DOI: 10.1016/j.cell.2016.12.012
PMCID: PMC5268070

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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