Article
Beta2-glycoprotein I and its clinical significance: from gene sequence to protein levels.
Autoimmunity reviews - 1 Sept 2007
Sodin-Semrl S, Rozman B
Abstract excerpt
In order to elucidate beta2-GPI at the DNA level and characterize its polymorphisms, mRNA expression, protein levels and clinical significance at each of these steps, a molecular review of beta2-GPI literature was performed. The human beta2-GPI complete nucleotide sequence has been reported and it consists of 8 exons separated by large introns. The beta2-GPI gene is polymorphic with four alleles. The distribution...
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