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Article

Association of estrogen receptor-alpha gene polymorphisms with stroke risk in patients with metabolic syndrome.

Acta neurologica Scandinavica - 1 Mar 2008

Lazaros L, Markoula S, Xita N, Giannopoulos S, Gogou P, Lagos G, Kyritsis A P, Georgiou I

Abstract excerpt

OBJECTIVE: The vascular protective effects of estrogens are mediated by their binding to the two known estrogen receptors. In this study, we examine the association of stroke with two common polymorphisms of the ESR1 gene in patients with metabolic syndrome. MATERIALS AND METHODS: DNA from 130 patients hospitalized for ischemic stroke and 240 healthy controls were genotyped for ESR1 PvuII and XbaI polymorphisms....

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 17854418
DOI: 10.1111/j.1600-0404.2007.00926.x

Genes

ESR1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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