Article
Estrogen receptor α genetic variants and the risk of stroke in a South Indian population from Andhra Pradesh.
Clinica chimica acta; international journal of clinical chemistry - 11 Nov 2010
Munshi Anjana, Sharma Vandana, Kaul Subhash, Al-Hazzani Amal, Alshatwi Ali A, Manohar V Raj, Rajeshwar K, Babu M Sai, Jyothy A
Abstract excerpt
BACKGROUND: Stroke is a complex disease caused by combination of multiple risk factors. Recent findings have suggested that stroke has a strong genetic component. Evidence suggests that variations in the estrogen receptor α (ESR1) gene may influence stroke risk. AIMS: The present study was carried out to investigate the role of ESR1 gene polymorphisms [PvuII (rs 2234693) and XbaI (rs 9340799)] with stroke in a...
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