Article
Associations of ESR2 AluI (G/A) polymorphism with ischemic stroke in Caucasians.
Journal of the neurological sciences - 15 May 2012
Markoula Sofia, Milionis Haralampos, Lazaros Leandros, Spengos Konstantinos, Vassilopoulou Sofia, Chatzistefanidis Dimitrios, Kargiotis Odysseas, Georgiou Ioannis, Kyritsis Athanassios P
Abstract excerpt
Raising interest towards genes implicates the effect of estrogen receptor-alpha (ESR1) gene on cerebrovascular disease, but data are lacking regarding the effect of estrogen receptor-beta (ESR2) gene. We assessed the hypothesis that AluI (G/A) polymorphism of the ESR2 gene (rs 4986938) is associated with ischemic stroke in a Caucasian population. Four hundred twenty four consecutive stroke patients and 430 age...
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