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Article

Variation in the estrogen receptor alpha gene and risk of stroke: the Rotterdam Study.

Stroke - 1 Apr 2008

Bos Michiel J, Schuit Stephanie C E, Koudstaal Peter J, Hofman Albert, Uitterlinden André G, Breteler Monique M B

Abstract excerpt

BACKGROUND AND PURPOSE: Variations in the -397T>C (rs2234693) and -351A>G (rs9340799) single nucleotide polymorphisms of the estrogen alpha receptor (ESR1) gene were found to be strongly associated with risk of ischemic heart disease, although not all studies could replicate this finding. One study also reported an association with stroke. We assessed whether variations in the ESR1 gene are associated with the...

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Identifiers

PMID: 18309176
DOI: 10.1161/STROKEAHA.107.494476

Genes

ESR1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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