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Article

Epidermal growth factor (EGF) A61G polymorphism and EGF gene expression in normal colon tissue from patients with colorectal cancer.

Acta oncologica (Stockholm, Sweden) - 1 Jan 2007

Spindler Karen-Lise G, Nielsen Jens N, Ornskov Dorthe, Brandslund Ivan, Jakobsen Anders

Abstract excerpt

INTRODUCTION: EGF/EGFR interactions are important mechanisms behind colorectal tumour development and growth. Recently a single nucleotide polymorphism in the EGF gene has been identified (EGF A61G). It may be a potential predictor for survival of patients receiving EGFR-inhibitor cetuximab treatment, but the clinical importance and the functional influence on EGF gene expression levels in colorectal cancer (CRC)...

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Source

Identifiers

PMID: 17851837
DOI: 10.1080/02841860701338853

Genes

EGF
EGFR

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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