Article
Derepression of microRNA-mediated protein translation inhibition by apolipoprotein B mRNA-editing enzyme catalytic polypeptide-like 3G (APOBEC3G) and its family members.
The Journal of biological chemistry - 16 Nov 2007
Huang Jialing, Liang Zhihui, Yang Bin, Tian Heng, Ma Jin, Zhang Hui
Abstract excerpt
The apolipoprotein B mRNA-editing enzyme catalytic polypeptide-like 3G (APOBEC3G or A3G) and its fellow cytidine deaminase family members are potent restrictive factors for human immunodeficiency virus type 1 (HIV-1) and many other retroviruses. A3G interacts with a vast spectrum of RNA-binding proteins and is located in processing bodies and stress granules. However, its cellular function remains to be further...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
