Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Enterovirus 71 antagonizes the inhibition of the host intrinsic antiviral factor A3G

11 Sept 2018

Abstract excerpt

Although the host restriction factor APOBEC3G (A3G) has broad spectrum antiviral activity, whether A3G inhibits enterovirus 71 (EV71) has been unclear until now. In this study, we demonstrated for the first time that A3G could inhibit EV71 virus replication. Silencing A3G in H9 cells enhanced EV71 replication, and EV71 replication was lower in H9 cells expressing A3G than in Jurkat cells without A3G expression,...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Animal Disease Management and Epidemiology
Share to Viral gastroenteritis research and epidemiology
Share to Viral Infections and Immunology Research

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 30247716
DOI: 10.1093/nar/gky840

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Enterovirus 71 antagonizes the inhibition of the host intrinsic antiviral factor A3GPMID 30247716Read ↗

Beclin1 Binds to Enterovirus 71 3D Protein to Promote the Virus ReplicationSemantic proximity Read ↗

Staufen1 Protein Participates Positively in the Viral RNA Replication of Enterovirus 71Semantic proximity Read ↗

Enterovirus 71 induces autophagy by regulating has-miR-30a expression to promote viral replicationSemantic proximity Read ↗

PolyC-Binding Protein 1 Interacts with 5′-Untranslated Region of Enterovirus 71 RNA in Membrane-Associated Complex to Facilitate Viral ReplicationSemantic proximity Read ↗

Polypyrimidine Tract-Binding Protein Regulates Enterovirus 71 Translation Through Interaction with the Internal Ribosomal Entry SiteSemantic proximity Read ↗

N4-acetylcytidine regulates the replication and pathogenicity of enterovirus 71Semantic proximity Read ↗

MicroRNA-23b Inhibits Enterovirus 71 Replication through Downregulation of EV71 VPl ProteinSemantic proximity Read ↗

Downregulation of miR-155-5p facilitates enterovirus 71 replication through suppression of type I IFN response by targeting FOXO3/IRF7 pathwaySemantic proximity Read ↗

EV-D68 cleaves LARP1 and PABPC1 by 3Cpro to redirect host mRNA translation machinery toward its genomic RNASemantic proximity Read ↗

Human Virus-Derived Small RNAs Can Confer Antiviral Immunity in Mammals.Semantic proximity Read ↗

Identification of microRNAs Involved in the Host Response to Enterovirus 71 Infection by a Deep Sequencing ApproachSemantic proximity Read ↗

MicroRNA and Pathogenesis of Enterovirus InfectionSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.