Article
When Poly(A) Binding Proteins Meet Viral Infections, Including SARS-CoV-2
16 Mar 2022
Abstract excerpt
Viruses have evolved diverse strategies to hijack the cellular gene expression system for their replication. The poly(A) binding proteins (PABPs), a family of critical gene expression factors, are viruses' common targets. PABPs act not only as a translation factor but also as a key factor of mRNA metabolism. During viral infections, the activities of PABPs are manipulated by various viruses, subverting the host...
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