Article
Identification of type 2 diabetes genes in Mexican Americans through genome-wide association studies.
Diabetes - 1 Dec 2007
Hayes M Geoffrey, Pluzhnikov Anna, Miyake Kazuaki, Sun Ying, Ng Maggie C Y, Roe Cheryl A, Below Jennifer E, Nicolae Raluca I, Konkashbaev Anuar, Bell Graeme I, Cox Nancy J, Hanis Craig L
Abstract excerpt
OBJECTIVE: The objective of this study was to identify DNA polymorphisms associated with type 2 diabetes in a Mexican-American population. RESEARCH DESIGN AND METHODS: We genotyped 116,204 single nucleotide polymorphisms (SNPs) in 281 Mexican Americans with type 2 diabetes and 280 random Mexican Americans from Starr County, Texas, using the Affymetrix GeneChip Human Mapping 100K set. Allelic association exact...
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