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Genome-wide association study identifies novel risk variants from RPS6KA1, CADPS, VARS, and DHX58 for fasting plasma glucose in Arab population.

Scientific reports - 13 Jan 2020

Hebbar Prashantha, Abu-Farha Mohamed, Alkayal Fadi, Nizam Rasheeba, Elkum Naser, Melhem Motasem, John Sumi Elsa, Channanath Arshad, Abubaker Jehad, Bennakhi Abdullah, Al-Ozairi Ebaa, Tuomilehto Jaakko, Pitkaniemi Janne, Alsmadi Osama, Al-Mulla Fahd, Thanaraj Thangavel Alphonse

Abstract excerpt

Consanguineous populations of the Arabian Peninsula, which has seen an uncontrolled rise in type 2 diabetes incidence, are underrepresented in global studies on diabetes genetics. We performed a genome-wide association study on the quantitative trait of fasting plasma glucose (FPG) in unrelated Arab individuals from Kuwait (discovery-cohort:n = 1,353; replication-cohort:n = 1,196). Genome-wide genotyping in...

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PMID: 31932636
DOI: 10.1038/s41598-019-57072-9
PMCID: PMC6957513

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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