Article
Follow-up analysis of genome-wide association data identifies novel loci for type 1 diabetes.
Diabetes - 1 Jan 2009
Grant Struan F A, Qu Hui-Qi, Bradfield Jonathan P, Marchand Luc, Kim Cecilia E, Glessner Joseph T, Grabs Rosemarie, Taback Shayne P, Frackelton Edward C, Eckert Andrew W, Annaiah Kiran, Lawson Margaret L, Otieno F George, Santa Erin, Shaner Julie L, Smith Ryan M, Skraban Robert, Imielinski Marcin, Chiavacci Rosetta M, Grundmeier Robert W, Stanley Charles A, Kirsch Susan E, Waggott Daryl, Paterson Andrew D, Monos Dimitri S, Polychronakos Constantin, Hakonarson Hakon
Abstract excerpt
OBJECTIVE: Two recent genome-wide association (GWA) studies have revealed novel loci for type 1 diabetes, a common multifactorial disease with a strong genetic component. To fully utilize the GWA data that we had obtained by genotyping 563 type 1 diabetes probands and 1,146 control subjects, as well as 483 case subject-parent trios, using the Illumina HumanHap550 BeadChip, we designed a full stage 2 study to...
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