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Article

Influence of paternally imprinted genes on development.

Development (Cambridge, England) - 1 Oct 1991

Barton S C, Ferguson-Smith A C, Fundele R, Surani M A

Abstract excerpt

The parental origin of chromosomes is critical for normal development in the mouse because some genes are imprinted resulting in a predetermined preferential expression of one of the alleles. Duplication of the paternal (AG: androgenones) or maternal (GG/PG: gynogenones/parthenogenones) genomes will result in an excess or deficiency of gene dosage with corresponding phenotypic effects. Here, we report on the...

Topics

Animals
Blastocyst
Bone and Bones
Chimera
Genetic Engineering
Genome
Male
Mice
Mice, Transgenic
Microinjections
Phenotype

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 1782874
DOI: 10.1242/dev.113.2.679

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-1782874-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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