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Article

Androgenetic/biparental mosaicism causes placental mesenchymal dysplasia.

Journal of medical genetics - 1 Feb 2006

Kaiser-Rogers K A, McFadden D E, Livasy C A, Dansereau J, Jiang R, Knops J F, Lefebvre L, Rao K W, Robinson W P

Abstract excerpt

BACKGROUND: Placental mesenchymal dysplasia (PMD) is a distinct syndrome of unknown aetiology that is associated with significant fetal morbidity and mortality. Intrauterine growth restriction is common, yet, paradoxically, many of the associated fetuses/newborns have been diagnosed with Beckwith-Wiedemann syndrome (BWS). METHODS: We report two cases of PMD with high levels of androgenetic (complete paternal...

Topics

Adult
Androgens
Female
Genotype
Humans
Karyotyping
Mesoderm
Microsatellite Repeats
Mosaicism
Placenta Diseases
Pregnancy

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 15908568
DOI: 10.1136/jmg.2005.033571
PMCID: PMC2564642

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