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Article

Comparative analysis of mutants in the mycothiol biosynthesis pathway in Mycobacterium smegmatis.

Biochemical and biophysical research communications - 9 Nov 2007

Rawat Mamta, Johnson Chantale, Cadiz Vanessa, Av-Gay Yossef

Abstract excerpt

The role of mycothiol in mycobacteria was examined by comparative analysis of mutants disrupted in the four known genes encoding the protein machinery needed for mycothiol biosynthesis. These mutants were sensitive to acid stress, antibiotic stress, alkylating stress, and oxidative stress indicating that mycothiol and mycothiol-dependent enzymes protect the mycobacterial cell against attack from various different...

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PMID: 17826740
DOI: 10.1016/j.bbrc.2007.08.142

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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