Article
Cell wall structure of a mutant of Mycobacterium smegmatis defective in the biosynthesis of mycolic acids.
The Journal of biological chemistry - 10 Mar 2000
Wang L, Slayden R A, Barry C E, Liu J
Abstract excerpt
A mutant strain of Mycobacterium smegmatis defective in the biosynthesis of mycolic acids was recently isolated (Liu, J., and Nikaido, H. (1999) Proc. Natl. Acad. Sci. U. S. A. 96, 4011-4016). This mutant failed to synthesize full-length mycolic acids and accumulated a series of long chain beta-hydroxymeromycolates. In this work, we provide a detailed characterization of the localization of meromycolates and of...
Topics
- Calorimetry, Differential Scanning
- Cell Wall
- Chromatography, Thin Layer
- Galactans
- Magnetic Resonance Spectroscopy
- Mutation
- Mycobacterium smegmatis
- Mycolic Acids