Article
The glycosyltransferase gene encoding the enzyme catalyzing the first step of mycothiol biosynthesis (mshA).
Journal of bacteriology - 1 Jun 2003
Newton Gerald L, Koledin Teresa, Gorovitz Batia, Rawat Mamta, Fahey Robert C, Av-Gay Yossef
Abstract excerpt
Mycothiol is the major thiol present in most actinomycetes and is produced from the pseudodisaccharide 1D-myo-inosityl 2-acetamido-2-deoxy-alpha-D-glucopyranoside (GlcNAc-Ins). A transposon mutant of Mycobacterium smegmatis shown to be GlcNAc-Ins and mycothiol deficient was sequenced to identify...
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