Identifying novel mycobacterial stress associated genes using a random mutagenesis screen in Mycobacterium smegmatis.

Abstract excerpt

Cell envelope associated components of Mycobacterium tuberculosis (M.tb) have been implicated in stress response, immune modulation and in vivo survival of the pathogen. Although many such factors have been identified, there is a large disparity between the number of genes predicted to be involved in functions linked to the envelope and those described in the literature. To identify and characterise novel stress...

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