Article
Association analysis of HSP90B1 with bipolar disorder.
Journal of human genetics - 1 Jan 2007
Kakiuchi Chihiro, Ishiwata Mizuho, Nanko Shinichiro, Kunugi Hiroshi, Minabe Yoshio, Nakamura Kazuhiko, Mori Norio, Fujii Kumiko, Umekage Tadashi, Tochigi Mamoru, Kohda Kazuhisa, Sasaki Tsukasa, Yamada Kazuo, Yoshikawa Takeo, Kato Tadafumi
Abstract excerpt
Pathophysiological role of endoplasmic reticulum (ER) stress response signaling has been suggested for bipolar disorder. The goal of this study was to test the genetic association between bipolar disorder and an ER chaperone gene, HSP90B1 (GRP94/gp96), which is located on a candidate locus, 12q23.3. We tested the genetic association between bipolar disorder and HSP90B1 by case-control studies in two independent...
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